Meditope-enabled T cells
Grant
US12590137B2
Kind: B2
Mar 31, 2026
Assignee
CITY OF HOPE
Inventors
John C. Williams, Christine Brown, Kurt Jenkins, Yi-Chiu Kuo, Cheng-Fu Kuo
Abstract
Provided herein are compositions which exhibit novel therapeutic capabilities and allow to reduce the off-target effect of therapeutic antibodies. The compositions include recombinant proteins that if expressed by a T cell can efficiently recruit therapeutic antibodies to their site of action.
CPC Classifications
A61K 40/31
A61K 2239/28
A61K 2239/10
A61K 2239/11
A61K 2239/15
Filing Date
2018-12-31
Application No.
16958614
Claims
18