← USPTO Patent Grants

Inhibitors of spinster homolog 2 (SPNS2) for use in therapy

Grant US12590083B2 Kind: B2 Mar 31, 2026

Assignee

University of Virginia Patent Foundation

Inventors

Kevin R. Lynch, Yugesh Kharel, Webster L. Santos, Ashley Peralta, Russell G. Fritzemeier, Daniel Foster

Abstract

The present disclosure provides SPNS2 inhibitor compounds according to Formula I and their pharmaceutically acceptable salts, and/or tautomers as described in the disclosure, and the disclosure provides their pharmaceutical compositions and methods of use in therapy.

CPC Classifications

C07D 413/04 C07D 413/14 A61P 1/00 A61P 3/10 A61P 11/06 A61P 17/06 A61P 35/00 A61P 37/08

Filing Date

2020-01-22

Application No.

17310179

Claims

2