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PD-1/PD-L1 inhibitors

Grant US12590062B2 Kind: B2 Mar 31, 2026

Assignee

Gilead Sciences, Inc.

Inventors

Evangelos Aktoudianakis, Todd Appleby, Aesop Cho, Zhimin Du, Michael Graupe, Juan A. Guerrero, Salman Y. Jabri, Lateshkumar Thakorlal Lad, Paulo A. Machicao Tello, Jonathan William Medley, Samuel E. Metobo, Prasenjit Kumar Mukherjee, Devan Naduthambi, Gregory Notte, Eric Q. Parkhill, Barton W. Phillips, Scott Preston Simonovich, Neil H. Squires, Chandrasekar Venkataramani, Peiyuan Wang, William J. Watkins, Jie Xu, Kin Shing Yang, Christopher Allen Ziebenhaus

Abstract

Compounds according to formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.

CPC Classifications

A61K 31/5377 A61K 31/44 A61K 31/444 A61K 31/4545 A61K 31/497 A61K 45/06 C07D 213/85 C07D 295/088 C07D 491/107 C07D 401/12 C07D 405/12 C07D 413/12 C07D 213/69 C07D 213/30 C07D 213/61 C07D 213/64 C07D 401/04 C07D 401/14 C07D 405/14 C07D 487/08 C07D 487/10 C07D 498/04 C07D 519/00 C07D 417/14 C07D 487/04 C07D 471/04 A61P 35/02 A61P 35/00

Filing Date

2020-11-13

Application No.

17098171

Claims

18