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Use of D9-methadone for postoperative pain relief

Grant US12590054B2 Kind: B2 Mar 31, 2026

Assignee

Board of Regents, The University of Texas System

Inventors

Tatiana N. Nanovskaya, Jun-Ho La, Mahmoud S. Ahmed, Jigong Wang

Abstract

Certain embodiments are directed to the use of d9-methadone as an alternative formulation for methadone, the d9-methadone having an improved absorption-distribution-metabolism-excretion profile, analgetic efficacy, and safety for the management of pain following injury such as trauma, disease, and surgery.

CPC Classifications

A61K 31/137 A61K 45/06 A61P 25/04 C07B 59/001 C07C 225/06

Filing Date

2022-12-22

Application No.

18087350

Claims

15