Methods for treating bladder tumors with viral nanoparticle conjugates and immune checkpoint inhibitors
Grant
US12589165B2
Kind: B2
Mar 31, 2026
Assignee
The United States of America, as represented by the Secretary, Department of Health and Human Services
Inventors
Elisabet de los Pinos, John Todd Schiller, Rhonda C. Kines
Abstract
Some embodiments of the present disclosure are directed to methods and compositions for the treatment of tumors, using a combination of immunotherapeutic agents and tumor-targeting viral capsid protein assemblages comprising anti-cancer molecules conjugated to viral capsid proteins.
CPC Classifications
A61K 47/6901
A61K 39/3955
A61K 41/0061
A61K 41/0071
A61K 41/0076
A61K 2039/54
A61K 2039/545
A61K 39/39558
A61K 45/06
A61K 47/62
A61K 39/395
A61P 35/00
C12N 7/00
C12N 2710/20023
C12N 2710/20042
C12N 2710/20071
C07K 16/2818
C07K 16/2827
B82Y 5/00
Filing Date
2018-04-11
Application No.
16604790
Claims
20