Trans-cyclooctene prodrug of monomethyl auristatin E
Grant
US12589162B2
Kind: B2
Mar 31, 2026
Assignee
Tambo, Inc.
Inventors
Jose Manuel Mejia Oneto, Nathan A. Yee, Jesse M. McFarland
Abstract
6-(Carbonyloxy)-1-methylcyclooct-4-ene-1-carbonyl)-aspartic acid conjugate of monomethyl auristatin E may be used for bioorthogonal delivery to a targeted location in a subject in the treatment of cancer and tumor growths.
CPC Classifications
A61K 47/68
A61K 47/06
A61K 47/542
A61K 47/642
Filing Date
2021-08-06
Application No.
18020221
Claims
4