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CD71 binding fibronectin type III domains

Grant US12589159B2 Kind: B2 Mar 31, 2026

Assignee

ARO Biotherapeutics Company

Inventors

Russell C. Addis, Zhanna Druzina, Robert Kolakowski, Swapnil Kulkarni, Steven G. Nadler, Karyn O'Neil, Yao Xin

Abstract

The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind CD71, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the same.

CPC Classifications

C12N 2320/32 C12N 2310/14 C12N 2310/3513 C12N 2310/11 C12N 15/113 A61K 47/6435 A61K 31/7088 C07K 14/435

Filing Date

2023-02-27

Application No.

18174751

Claims

18