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Immunity-inducing agent comprising antigen peptide-adjuvant nucleotide conjugate and pharmaceutical composition comprising same

Grant US12589148B2 Kind: B2 Mar 31, 2026

Assignee

The University of Kitakyushu

Inventors

Shinichi Mochizuki, Makoto Koizumi, Koji Morita

Abstract

The present invention provides an immunity-inducing agent comprising, as an active component, a polynucleotide/peptide conjugate in which a single-chain polynucleotide or polynucleotide derivative comprising a CpG motif, and an antigenic peptide are bound via a spacer, wherein the spacer is covalently bound at one end thereof to the polynucleotide or polynucleotide derivative and covalently bound at the other end thereof to the antigenic peptide, as well as a pharmaceutical composition comprising said immunity-inducing agent.

CPC Classifications

A61K 39/39

Filing Date

2019-09-27

Application No.

17280605

Claims

27