Coating agent for inducing differentiation of pluripotent stem cells into brain microvascular endothelium-like cells and use thereof
Grant
US12584906B2
Kind: B2
Mar 24, 2026
Assignee
PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY
Inventors
Tamihide Matsunaga, Tadahiro Hashita, Hiromasa Aoki, Misaki Yamashita
Abstract
Provided is a technology allowing for stable supply of brain microvascular endothelium-like cells. This coating agent for inducing differentiation of pluripotent stem cells into brain microvascular endothelium-like cells contains at least one component of a Laminin-221 fragment or an N-terminal Vitronectin.
CPC Classifications
C12N 5/0696
C12N 5/0692
C12N 5/069
C12N 2533/54
C12N 2533/52
C12N 2501/115
C12N 2533/90
C12N 2500/99
C12N 2506/45
C12N 2537/10
C12M 23/10
C12M 23/20
G01N 33/5064
G01N 33/5082
Filing Date
2021-02-09
Application No.
17798206
Claims
4