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Method and kit for assembly of multiple DNA fragments at room temperature

Grant US12584155B2 Kind: B2 Mar 24, 2026

Assignee

UNIVERSITETET I TROMSØ—NORGES ARKTISKE UNIVERSITET

Inventors

Yvonne Piotrowski, Atle Noralf Larsen

Abstract

The present invention relates to recombinant DNA technology, in particular to methods for assembling two or more double stranded (ds) nucleic acid molecules with overlapping terminal sequences. In particular, the present invention relates to the use of a thermolabile DNA polymerase II derived 3′-5′ exonuclease isolated from Moritella viscoa and a thermolabile DNA polymerase I of marine origin in multi DNA assembly processes.

CPC Classifications

C12N 9/1252 C12Y 207/07007

Filing Date

2020-10-01

Application No.

17765710

Claims

13