KRAS G12C inhibitors and methods of using the same
Grant
US12583854B2
Kind: B2
Mar 24, 2026
Assignee
Amgen Inc.
Inventors
Jian Chen, Nuria A. Tamayo, Longbin Liu, Hui-Ling Wang, Brian Alan Lanman, Ryan Paul Wurz, Youngsook Shin, Victor J. Cee
Abstract
Provided herein are KRAS G12C inhibitors, such as composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
CPC Classifications
C07D 471/04
A61P 35/00
A61P 38/16
A61P 45/06
Filing Date
2021-09-22
Application No.
17482230
Claims
35