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Sulfur-containing compound based on glutarimide skeleton and application thereof

Grant US12582641B2 Kind: B2 Mar 24, 2026

Assignee

SHANGHAITECH UNIVERSITY

Inventors

Xiaobao Yang, Biao Jiang, Xing Qiu, Ning Sun, Renhong Sun, Linyi Liu, Chaowei Ren

Abstract

The present disclosure relates to a compound of Formula (I) or a salt, a solvate, an isotopically enriched analog, a tautomer, a polymorph, a stereoisomer thereof, or a mixture of stereoisomers thereof, and their use for treating a tumor. The present disclosure also relates to a compound of Formula (I′) or a pharmaceutically acceptable salt, a solvate, an isotopically enriched analog, a tautomer, a polymorph, a stereoisomer thereof, or a mixture of stereoisomers thereof, and their use for treating a tumor.

CPC Classifications

A61K 31/4545 A61K 31/454 A61K 31/4709 A61K 31/496 A61K 31/506 A61K 31/517 A61K 31/5377 A61K 31/541 A61K 31/55 A61K 31/551 A61K 45/06 A61P 35/00 A61P 7/06 A61P 35/02 C07D 401/04 C07D 401/14 C07D 405/14 C07D 409/14 C07D 413/14 C07D 471/04 C07D 471/08 C07D 491/107 C07D 417/14 C07D 453/02 C07D 487/08 C07F 9/65583 C07F 9/6558

Filing Date

2020-02-25

Application No.

17433462

Claims

53