Ophthalmic pharmaceutical composition containing a combination of brinzolamide and brimonidine and method of preparation thereof
Grant
US12582603B2
Kind: B2
Mar 24, 2026
Assignee
NTC S.r.l.
Inventors
Evangelos Karavas, Efthymios Koutris, Vasiliki Samara, Ioanna Koutri, Anastasia Kalaskani, Andreas Kakouris, Rumit Rajivbhai Shah
Abstract
The present invention relates to an ophthalmic aqueous composition for the decrease of intraocular pressure in patients with ocular hypertension or open angle glaucoma containing a combination of Brinzolamide and Brimonidine and a method for preparation thereof. The invention as currently presented has a significant advantage over ophthalmic compositions already known in the art. More particularly the present invention relates to a multi-dose ophthalmic aqueous composition comprising a borate, a single polyol and benzalkonium chloride as an antimicrobial agent.
CPC Classifications
A61K 9/08
A61K 9/0048
A61K 31/498
A61K 31/542
A61K 47/10
Filing Date
2018-11-06
Application No.
16761337
Claims
19