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Systems and methods for identifying progression of hypoxic-ischemic brain injury

Grant US12582345B2 Kind: B2 Mar 24, 2026

Assignee

The University of Chicago

Inventors

Jordan D. Fuhrman, Ali Mansour, Maryellen L. Giger, Fernando D. Goldenberg

Abstract

A method for identifying the presence or progression of hypoxic ischemic brain injury includes, for each subset of one or more subsets of a three-dimensional medical image of a head of a patient: (i) inputting said each subset into a machine-learning model, (ii) extracting one or more features or feature maps from the machine-learning model, and (iii) constructing, based on the one or more features or feature maps, one of a sequence of vectors. The sequence of vectors is then pooled to obtain a scan-level vector that is used to obtain a score indicating HIBI presence or progression in the patient. For example, the scan-level vector can be inputted into a pre-trained classifier that generates the score based on the scan-level vector. The machine-learning model may be a pre-trained conventional neural network or support vector machine.

CPC Classifications

A61B 5/4064 A61B 5/0042 G06T 7/0012 G06T 2207/10081 G06T 2207/20081 G06T 2207/20084 G06T 2207/30016 A61K 9/0097

Filing Date

2022-02-01

Application No.

18274819

Claims

20