Plasma piRNA combination for early diagnosis of gastric cancer and application thereof

Abstract

A plasma piwi-interacting RNA (piRNA) combination for early diagnosis of gastric cancer and application thereof are provided. Based on the plasma piRNA expression profile of the Chinese population, the present invention obtains a plasma piRNA combination for early diagnosis of gastric cancer, and establishes an early diagnosis model for gastric cancer based on the plasma piRNA combination. The model can predict the incidence risk of gastric cancer with relatively high accuracy, which helps to reduce the cost of detection. At the same time, the present invention uses a Lasso Logistic regression model, which greatly reduces the number of variables included in the model and facilitates the application and popularization of the model.

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