Single molecule peptide sequencing
Grant
US12578345B2
Kind: B2
Mar 17, 2026
Assignee
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Inventors
Edward Marcotte, Eric V. Anslyn, Andrew Ellington, Jagannath Swaminathan, Erik Hernandez, Amber Johnson, Alexander Boulgakov, James L. Bachman, Helen Seifert
Abstract
Methods of identifying a sequence of a polypeptide within a heterogenous mixture of polypeptides, the polypeptide being immobilized to a support and having at least one labeled amino acid residue. Methods involve detecting at least one signal or signal change from the immobilized polypeptide and subjecting the polypeptide to conditions sufficient to remove at least one amino acid residue from the polypeptide.
CPC Classifications
C07K 17/08
G01N 2570/00
G01N 33/58
G01N 33/582
G01N 33/68
G01N 33/6818
G01N 33/6824
Filing Date
2023-10-24
Application No.
18493207
Claims
21