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Engineered microorganisms and methods for improved aldehyde dehydrogenase activity

Grant US12577594B2 Kind: B2 Mar 17, 2026

Assignee

Genomatica, Inc.

Inventors

Amit M. Shah, Harish Nagarajan

Abstract

Disclosed are biosynthetic methods and engineered microorganism that enhance or improve the biosynthesis of hexamethylenediamine, caproic acid or caprolactam. The engineered microorganisms include selected aldehyde dehydrogenase activity.

CPC Classifications

C12P 13/001 C12P 7/18 C12P 7/40 C12P 7/44 C12P 7/62 C12P 13/005 C12P 17/10 C12N 1/20 C12N 9/0008 C12N 9/001 C12N 9/1096 C12N 15/52 C12N 15/70 C12Y 103/01044 C12Y 206/01 C12Y 103/01038

Filing Date

2020-04-24

Application No.

17605196

Claims

13