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Perturbation beads for use in assays

Grant US12577556B2 Kind: B2 Mar 17, 2026

Assignee

Zafrens Inc.

Inventors

Kandaswamy Vijayan, Ravi Ramenani, Chulmin Choi, Aurelien Laguerre, Gopichandran Ravichandran, Nicholas Sam-Soon, Yi Zhang, David Milliken, Kenneth Chng, Maina Ndungu

Abstract

Disclosed are uniquely labeled perturbation beads used alone or in combination with a capture bead. These perturbation beads are useful in drug discovery especially in assays conducted in a mapped assay device. Such a uniquely labeled perturbation bead, when used in an examination area of a mapped assay device, allows for correlating the sequence of nucleic acids and other components from a lysed cell to the specific examination area where the nucleic acid was retrieved.

CPC Classifications

C12N 15/10 C12N 15/1065

Filing Date

2024-06-05

Application No.

18734832

Claims

11