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Anti-TROP2 antibody

Grant US12577319B2 Kind: B2 Mar 17, 2026

Assignee

SYSTIMMUNE, INC.

Inventors

Yi Zhu, Yong Zhang, Shi Zhuo, Muran Ding, Zun Wang

Abstract

The present disclosure relates to antibodies, in particular monoclonal antibodies of murine, chimeric, and humanized origin, that specifically bind to the human TROP2 protein, and to the amino acid and nucleotide sequences encoding these antibodies. The disclosure also discloses the use of these antibodies as a diagnostic reagent or a drug in the diagnostic and/or therapeutic management of malignancies or any lesion related to the overexpression of the receptor.

CPC Classifications

C07K 16/30

Filing Date

2021-06-18

Application No.

18011175

Claims

19