Anti-BCMA/anti-4-1BB bispecific antibodies and uses thereof
Grant
US12577314B2
Kind: B2
Mar 17, 2026
Assignee
ABL BIO INC.
Inventors
Kyung Jin Park, Yang Soon Lee, Sae Yi Lim, Hye Jin Chung, Kyeong Su Park, Yong Gyu Son, Seong Gyu Seon, Won Jun Son, Eun Jung Kim, Jae Hyun Eom, Ui Jung Jung, Min Ji Park, Jung Hyeon Hong
Abstract
An anti-B-cell maturation antigen (BCMA)/anti-4-1BB bispecific antibody or an antigen-binding fragment thereof, and use thereof, are provided. The bispecific antibody or an antigen-binding fragment thereof may have high binding affinity to both of a BCMA protein and a 4-1BB protein and may be effectively used to prevent or treat a disease related to BCMA, 4-1BB, or both thereof.
CPC Classifications
C07K 16/468
C07K 16/2878
A61P 35/00
Filing Date
2020-12-10
Application No.
17783344
Claims
11