Chimeric antigen receptor factories and methods of use thereof
Grant
US12577311B2
Kind: B2
Mar 17, 2026
Assignee
Dana-Farber Cancer Institute, Inc.
Inventors
Wayne A. Marasco, Quan Karen Zhu, Yufei Wang, Matthew Chang
Abstract
This invention is directed to chimeric antigen receptors and cells comprising the same, wherein the cells further secrete monoclonal antibodies locally at a tumor site.
CPC Classifications
C07K 16/2875
C07K 16/30
C07K 2317/31
C07K 2317/622
A61K 40/11
A61K 40/31
A61K 40/4232
A61K 2239/13
A61K 2239/28
A61K 2239/29
A61K 39/4631
A61P 35/00
Filing Date
2019-12-02
Application No.
17298271
Claims
10