Neutralizing antibodies to human endothelin
Grant
US12577300B2
Kind: B2
Mar 17, 2026
Assignee
Father Flanagan's Boys' Home Business
Inventors
Dominic Cosgrove
Abstract
This application provides antibodies and functional equivalents thereof which are capable of neutralizing endothelin-1, as well as their use in the treatment of disease conditions associated with endothelin-1 activation, such as Alport syndrome.
CPC Classifications
C07K 14/57536
C07K 16/26
A61K 39/3955
A61P 9/08
A61P 13/12
Filing Date
2021-12-20
Application No.
17645211
Claims
23