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Anti-IL-27 antibodies and uses thereof

Grant US12577299B2 Kind: B2 Mar 17, 2026

Assignee

SURFACE ONCOLOGY, LLC

Inventors

Alison O'Neill, Lauren Harshman, Jonathan Hill, Jou-Ku Chung, Kerry White, Robert Ross, Benjamin Lee

Abstract

The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof at a dose of at least about 0.003 mg/kg to at least about 20 mg/kg.

CPC Classifications

A61P 35/00 A61K 2039/505 A61K 2039/545 C07K 16/244 C07K 2317/565 C07K 2317/76 C07K 2317/92

Filing Date

2022-05-06

Application No.

17738927

Claims

22