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Influenza virus vaccines and uses thereof

Grant US12577279B2 Kind: B2 Mar 17, 2026

Assignee

Janssen Vaccines & Prevention B.V.

Inventors

Boerries Brandenburg, Johannes Petrus Maria Langedijk, Tina Ritschel, Ferdinand Jacobus Milder, Mandy Antonia Catharina Jongeneelen

Abstract

Provided herein are isolated mutant influenza hemagglutinin polypeptides, methods for providing isolated mutant hemagglutinin polypeptides, compositions comprising the same, vaccines comprising the same and methods of their use, in particular in the detection, prevention and/or treatment of influenza.

CPC Classifications

C07K 14/005 A61K 39/00 A61K 2039/575 A61K 39/12 A61K 39/145 C12N 2760/16222 C12N 2760/16234 A61P 31/16

Filing Date

2020-10-15

Application No.

17754922

Claims

39