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Manufacture of glucagon peptides

Grant US12577274B2 Kind: B2 Mar 17, 2026

Assignee

BACHEM HOLDING AG

Inventors

Ralf Eisenhuth, Guenther Loidl, Daniel Samson, Ralph O. Schoenleber

Abstract

The present invention refers to a method of purifying a glucagon peptide, the method comprising a two dimensional reversed phase high performance liquid chromatography protocol, wherein the first step is carried out at using a mobile phase comprising a triethylammonium phosphate (TEAP) buffer and acetonitrile, and the second step is carried out at using a mobile phase comprising aqueous acetic acid and acetonitrile.

CPC Classifications

C07K 1/20 C07K 1/18 C07K 14/605

Filing Date

2019-01-30

Application No.

16962793

Claims

21