Pyrimidine compounds for use as MAP4K1 inhibitors
Grant
US12577267B2
Kind: B2
Mar 17, 2026
Assignee
Glenmark Speciality S.A.
Inventors
Pravin Iyer, Sanjib Das, Murugan Chinnapattu, Sachin Chaudhari, Jagmohan Saini, Sravan Mandadi, Nagaraj Gowda, Dnyaneshwar Dahale, Sandip Patil, Nanasaheb Kadlag, Chandrasekhar Misra, Priyanka Pangare
Abstract
The present disclosure is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, which are useful as MAP4K1 inhibitors, processes for their preparation, pharmaceutical compositions comprising the compounds, and the use of the compounds or the compositions in the treatment or prevention of various diseases, conditions and/or disorders mediated by MAP4K1.
CPC Classifications
C07F 9/65583
C07F 9/6561
C07F 9/65586
A61P 35/00
C07B 2200/05
A61K 31/675
Filing Date
2022-07-06
Application No.
17912729
Claims
30