Functionalized gold carbene napthaquinone complexes for use in the treatment of cancer
Grant
US12577262B2
Kind: B2
Mar 17, 2026
Assignee
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Inventors
Jonathan L. Sessler, Sajal Sen, Jonathan F. Arambula, Zhengrong Cui
Abstract
The present disclosure relates to functionalized gold carbene naphthoquinone compounds and salts thereof. In some aspects, these compounds can be used to treat cancer including cancers which are resistant to one or more other chemotherapeutic agents such as cisplatin or platinum chemotherapeutic agents. Also provided herein are pharmaceutical compositions comprising the gold carbene naphthoquinone compounds. The present disclosure also provides methods of preparing a cancer vaccine.
CPC Classifications
C07F 1/10
C07F 1/12
A61K 31/4178
A61K 31/4184
A61P 33/00
A61P 35/00
Filing Date
2020-05-22
Application No.
17595670
Claims
17