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Macrocyclic compound

Grant US12577258B2 Kind: B2 Mar 17, 2026

Assignee

VERNALIS (R&D) LIMITED

Inventors

Takahiko Ito, Misato Takashima, Masakazu Atobe, Koichiro Arai, Tomohisa Toyama, Yu Yoshii, Andrew John Potter, Daniel Paul Maddox, Stuart Ray, Nicolas Foloppe

Abstract

A compound represented by the general formula (1) or a salt thereof, which has a superior IRAK-4 inhibitory activity, and is useful as active ingredients of medicaments for prophylactic treatment and/or therapeutic treatment of diseases relating to IRAK-4 inhibition.

CPC Classifications

C07D 471/18 C07D 498/18

Filing Date

2020-09-30

Application No.

18028578

Claims

19