← USPTO Patent Grants

Aryl receptor modulators and methods of making and using the same

Grant US12577256B2 Kind: B2 Mar 17, 2026

Assignee

Nogra Pharma Limited

Inventors

Francesca Viti, Salvatore Bellinvia, Salvatore Demartis

Abstract

The present invention is generally directed towards compounds capable of binding the aryl hydrocarbon receptor and modulating its activity, methods of treating inflammatory conditions such as Crohn's disease using such compounds, and pharmaceutical compositions comprising such compounds. Also provided are methods of increasing levels of IL-22 in a subject and/or decreasing levels of IFN-7 in a subject.

CPC Classifications

C07D 495/14

Filing Date

2024-05-07

Application No.

18656965

Claims

6