1,2,4-triazolone derivative as DHODH inhibitor, and preparation method therefor and use thereof
Grant
US12577250B2
Kind: B2
Mar 17, 2026
Assignee
WIGEN BIOMEDICINE TECHNOLOGY (SHANGHAI) CO., LTD.
Inventors
Yuli Xie, Houxing Fan, Lihui Qian
Abstract
The present invention relates to a 1,2,4-triazolone derivative as a DHODH inhibitor, a preparation method therefor and use thereof. Specifically, the present invention relates to a compound of general formula (1), a preparation method therefor, and use of the compound of general formula (1) and an isomer, a crystalline form, a pharmaceutically acceptable salt, a hydrate or a solvate thereof as a DHODH inhibitor in the treatment of DHODH-related diseases.
CPC Classifications
A61K 31/4196
A61K 31/437
A61K 31/444
A61K 31/55
C07D 471/04
C07D 487/04
A61P 35/00
Filing Date
2022-07-05
Application No.
18288803
Claims
6