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GCN2 and perk kinase inhibitors and methods of use thereof

Grant US12577249B2 Kind: B2 Mar 17, 2026

Assignee

Deciphera Pharmaceuticals, LLC

Inventors

Yu Mi Ahn, Gada Al-Ani, Daniel L. Flynn, Salim Javed, Patrick Kearney, Bertrand LeBourdonnec, Kristen Stoltz, Jeffery Zwicker

Abstract

Described herein are compounds that are inhibitors of GCN2 kinase or PERK kinase, and methods of treating diseases, including diseases associated with GCN2 kinase or PERK kinase, with said compounds.

CPC Classifications

C07D 487/04 A61P 35/00 A61K 45/06

Filing Date

2022-12-02

Application No.

18073886

Claims

28