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Antiviral heteroaryl ketone derivatives

Grant US12577240B2 Kind: B2 Mar 17, 2026

Assignee

Pfizer Inc.

Inventors

Dafydd Rhys Owen, Martin Youngjin Pettersson, Matthew Richard Reese, Matthew Forrest Sammons, Jamison Bryce Tuttle, Qingyi Yang

Abstract

The invention relates to compounds of Formula I wherein R1, R2, p, m, A, Z1, Z2, Z3 and Z4 are as defined herein, pharmaceutical compositions comprising the compounds, methods of treating COVID-19 in a patient by administering therapeutically effective amounts of the compounds, and methods of inhibiting or preventing replication of SARS-CoV-2 with the compounds.

CPC Classifications

C07D 417/14 A61P 31/14

Filing Date

2021-07-07

Application No.

18004996

Claims

27