Solid forms of APOL1 inhibitor and methods of using same
Grant
US12577233B2
Kind: B2
Mar 17, 2026
Assignee
Vertex Pharmaceuticals Incorporated
Inventors
Kevin James Gagnon, Jicong Li, Ales Medek, Jack Raphael Minchom, Yi Shi, Muna Shrestha, Faith Witkos
Abstract
The disclosure provides novel solid state forms of Compound I selected from ethanol solvate Form A, ethanol solvate Form B, citric acid cocrystal Form A, and Form B, compositions comprising the same, and methods of making and using the same, including use in treating APOL1 mediated kidney disease. (I).
CPC Classifications
C07D 403/12
C07B 2200/13
Filing Date
2021-06-11
Application No.
18001371
Claims
28