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Methods of preparing N6-((2-azidoethoxy)carbonyl)lysine

Grant US12577197B2 Kind: B2 Mar 17, 2026

Assignee

SANOFI

Inventors

Hans Aerni, Randall Scheuerman, Nikolai F. Sepetov, Alexander V. Shirokov

Abstract

Disclosed herein are methods of preparing N6-((2-azidoethoxy)carbonyl)lysine, N6-((2-azidoethoxy)carbonyl)-L-lysine, and N6-((2-azidoethoxy)carbonyl)-D-lysine. Also disclosed herein are the compounds tert-butyl N2-(tert-butoxycarbonyl)-N6-((2-chloroethoxy)carbonyl)-L-lysinate and tert-butyl N6-((2-azidoethoxy)carbonyl)-N2-(tert-butoxycarbonyl)-L-lysinate, and uses thereof.

CPC Classifications

C07C 247/22 C07D 207/404

Filing Date

2022-06-21

Application No.

17845495

Claims

30