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Systems and methods for the conditioning of cerebrospinal fluid

Grant US12576251B2 Kind: B2 Mar 17, 2026

Assignee

PHARAOH NEURO, INC.

Inventors

Blake Hedstrom, Shivanand P. Lad, Aaron McCabe, Emily Meyering, Jack Mondry, Amrita Sawhney, Elizabeth Scheurer, Matthew Stoll, Abhi Vase

Abstract

Systems and methods for treating biologic fluids are disclosed. Some disclosed embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject, heat CSF to a target temperature, cool CSF to a target temperature, apply light treatment to CSF, separate cells via their dielectric properties, apply spiral and/or centrifugal separation, introduce additives to target particles, and/or apply combinations thereof. The method may include the steps of withdrawing fluid comprising CSF, treating the fluid, and returning a portion of the treated fluid to the subject. During operation of the system, various parameters may be modified, such as flow rate.

CPC Classifications

A61M 27/006 A61M 2025/0031 A61M 2205/053 A61M 2205/054 A61M 2205/3344 A61M 2205/36 A61M 2205/50 A61M 2205/75 A61M 2230/005 A61M 2027/004 A61M 2202/0464

Filing Date

2023-02-03

Application No.

18105668

Claims

20