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Peptide PET/SPECT probes specific to oncoproteins in tumor extracellular matrix

Grant US12576168B2 Kind: B2 Mar 17, 2026

Assignee

CASE WESTERN RESERVE UNIVERSITY

Inventors

Zheng-Rong Lu, Songqi Gao

Abstract

A PET/SPECT probe includes the following formula: P-L-C wherein P is a EDB-FN targeting peptide, C is a PET/SPECT contrast agent; and L is an optional linker that covalently links the peptide to the contrast agent.

CPC Classifications

A61K 51/00 A61K 51/04 A61K 51/0474 A61K 51/08 A61K 51/088

Filing Date

2020-01-17

Application No.

17424104

Claims

13