Bispecific nanoparticle systems for targeting cancer cells
Grant
US12576160B2
Kind: B2
Mar 17, 2026
Assignee
University of Notre Dame du Lac
Inventors
Prakash Daniel Nallathamby
Abstract
Described herein are compositions and methods for targeting cancer cells and inducing cell death. In one embodiment, the composition comprises a nanoparticle system comprising a plurality of antibodies that recognize CAR-T cells and a plurality of antibodies that recognize cancer cells. The composition targets CAR-T cells to the vicinity of cancer cells, whereby upon activation, the CAR-T cells can effectuate cancer cell death.
CPC Classifications
A61K 47/6929
Filing Date
2022-05-06
Application No.
18547664
Claims
12