Compound comprising self-immolative group and ligand-drug conjugate comprising same
Grant
US12576156B2
Kind: B2
Mar 17, 2026
Assignee
TRIOAR, INC.
Inventors
Sung Ho Woo, Su Ho Park, Jong Un Cho, Sang Hyeon Yun, Gyoung Wook Min, Ok Ku Park, Hyun Mi Lee
Abstract
The present invention provides a compound comprising a self-immolative group and a ligand-drug conjugate comprising the same. According to the present invention, an active substance can be stably delivered to a target site, and the active substance can be rapidly released at the target site, thereby increasing the efficacy of the active substance, and the active substance can be inhibited from causing side effects at a location other than the target location.
CPC Classifications
A61K 47/549
A61K 47/6889
Filing Date
2024-11-22
Application No.
18957012
Claims
20