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Compositions and methods for anti-TnMUC1 gold CAR t-cells

Grant US12576135B2 Kind: B2 Mar 17, 2026

Inventors

Benjamin Wang, Gusti Zeiner, Albert Gacerez, Eytan Herzig

Abstract

Methods and compositions for delivering a payload at TnMUC1 positive cancer cells. Anti-TnMUC1 CARs and transgene payloads can be engineered into immune cells so that the transgene payload is expressed and delivered at desired times from the immune cell. Such anti-TnMUC1 CAR T-cells with transgene payloads can be combined with the administration of other molecules, e.g., other therapeutics such as anticancer therapies.

CPC Classifications

A61K 40/11 A61K 40/31 A61K 40/4257 A61K 38/208 A61P 35/00 A61P 1/18 A61P 13/08

Filing Date

2022-09-21

Application No.

17934091

Claims

17