Compositions and methods for anti-TnMUC1 gold CAR t-cells
Grant
US12576135B2
Kind: B2
Mar 17, 2026
Inventors
Benjamin Wang, Gusti Zeiner, Albert Gacerez, Eytan Herzig
Abstract
Methods and compositions for delivering a payload at TnMUC1 positive cancer cells. Anti-TnMUC1 CARs and transgene payloads can be engineered into immune cells so that the transgene payload is expressed and delivered at desired times from the immune cell. Such anti-TnMUC1 CAR T-cells with transgene payloads can be combined with the administration of other molecules, e.g., other therapeutics such as anticancer therapies.
CPC Classifications
A61K 40/11
A61K 40/31
A61K 40/4257
A61K 38/208
A61P 35/00
A61P 1/18
A61P 13/08
Filing Date
2022-09-21
Application No.
17934091
Claims
17