Combination therapy for cancer
Grant
US12576122B2
Kind: B2
Mar 17, 2026
Assignee
UNITED ARAB EMIRATES UNIVERSITY
Inventors
Amr Amin
Abstract
Methods of treating, suppressing, or reducing the severity of a liver cancer in a subject are described herein. The disclosed methods include administering to the subject a first amount of safranal or a pharmaceutically acceptable pro-drug thereof and administering to the subject a second amount of a TOP1 inhibitor. In some embodiments, the TOP1 inhibitor is irinotecan, topotecan, camptothecin, lamellarin D, and/or combinations thereof.
CPC Classifications
A61K 31/4745
A61K 31/11
A61K 31/44
A61K 36/88
A61P 35/00
Filing Date
2019-02-11
Application No.
16272515
Claims
3