Nucleic acid agents modulating SLAMF6 isoforms
Grant
US12576100B2
Kind: B2
Mar 17, 2026
Assignee
HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD.
Inventors
Michal Lotem, Emma Hajaj, Galit Eisenberg
Abstract
The invention relates to nucleic acid agents modulating the expression of SLAMF6 isoforms, compositions comprising same and methods for their use in immunomodulation. Specifically, provided are splice-switching oligonucleotides and constructs useful in cancer immunotherapy.
CPC Classifications
C12N 15/113
A61K 40/32
Filing Date
2020-06-23
Application No.
17622224
Claims
21