Ribose-modified cap analog and use thereof
Grant
US12576099B2
Kind: B2
Mar 17, 2026
Assignee
Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd.
Inventors
Honglei Zhang, Gengshen Song, Yangjian Liu, Kai Dong, Yuqing Ma, Chao Zhang, Yanfeng Wang, Guoliang Zhang, Lili Jiang, Jinyu Zhang
Abstract
The present disclosure provides a ribose-modified cap analog and a use thereof, and belongs to the technical field of chemical and biological engineering. The ribose-modified cap analog has a structure of formula (I). The ribose-modified cap analog described herein can improve the stability of mRNA and/or the translation efficiency of mRNA.
CPC Classifications
A61K 31/7105
A61K 31/7089
A61K 9/1272
A61K 9/5123
C07H 21/02
C12N 15/67
Filing Date
2025-02-28
Application No.
19066352
Claims
5