Oral brexanolone compositions and methods of preparation and use
Grant
US12576090B1
Kind: B1
Mar 17, 2026
Inventors
Nachiappan Chidambaram, Mahesh V. Patel, Jonathan Ogle, Kongnara Papangkorn, Samuel Akapo, Joel Frank, Benjamin J. Bruno
Abstract
Disclosed is a method and a brexanolone containing oral composition for treating CNS disorders such as depression. An embodiment of the invention comprises orally administering a brexanolone containing composition to a subject having a CNS disorder. The composition and methods disclosed herein exhibit effective oral absorption/bioavailability and a predetermined ratio of bioavailability in a fed state administration relative to a fasted state administration.
CPC Classifications
A61K 31/57
A61P 25/24
Filing Date
2024-11-18
Application No.
18950383
Claims
30