Methods for treating cholestasis
Grant
US12576079B2
Kind: B2
Mar 17, 2026
Inventors
Thomas Jaecklin, Alejandro Dorenbaum
Abstract
Provided herein are methods for treating cholestasis in a subject having a liver disease. The method includes administering to the subject an Apical Sodium-dependent Bile Acid Transporter (ASBTI). More specifically, the present invention relates to methods for treating cholestasis in a subject where the method includes administering an ASBTI to a subject at a dose of at least 10 μg/kg/day.
CPC Classifications
A61K 31/4995
A61K 31/554
A61K 31/7042
A61K 38/05
A61K 38/10
A61P 1/16
A61P 17/04
G01N 33/6893
G01N 2800/085
C12N 15/11
C12N 15/113
C12Q 2600/106
C12Q 2600/156
C12Q 1/6883
Filing Date
2020-12-11
Application No.
17119132
Claims
15