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Compositions and methods for treating slow-flow vascular malformations

Grant US12576069B2 Kind: B2 Mar 17, 2026

Assignee

Yale University

Inventors

Naiem Nassiri, Prashant Patel

Abstract

The disclosure relates in part to the discovery that slow-flow vascular malformations (which can be venous and/or lymphatic) can be treated using direct intralesional delivery of an active drug, such as but not limited to a mTOR inhibitor, such as but not limited to temsirolimus, or a salt or solvate thereof.

CPC Classifications

A61K 31/436

Filing Date

2020-09-10

Application No.

17642138

Claims

17