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Methods and compositions for treatment of inflammatory disease

Grant US12576059B2 Kind: B2 Mar 17, 2026

Inventors

Mikhail S. Shchepinov

Abstract

Disclosed herein are compositions and methods for controlling chronic inflammation in a patient. The compositions and methods employ D6-arachidonic acid or an ester thereof (D6-AA) as an anti-inflammatory agent that provides for significant reduction in inflammatory processes. In addition. The compositions of deuterated arachidonic acid or ester thereof comprise, on average, at least about 80% of the hydrogen atoms at each of the bis-allylic sites having been replaced by deuterium atoms and, on average, no more than about 30% of the hydrogen atoms at the mono-allylic sites having been replaced by deuterium atoms.

CPC Classifications

A61K 31/202

Filing Date

2024-03-21

Application No.

18612000

Claims

6