Compositions for delivery of codon-optimized mRNA
Grant
US12576030B2
Kind: B2
Mar 17, 2026
Assignee
Translate Bio, Inc.
Inventors
John Androsavich, Lianne Boeglin, Shraddha Sharma, Gang Sun, Neha Kaushal, Shrirang Karve
Abstract
The present invention provides, among other things, improved pharmaceutical compositions comprising codon-optimized mRNA encoding a peptide or polypeptide encapsulated in a lipid nanoparticle comprising one or more of the cationic lipids that are particularly effective for pulmonary delivery.
CPC Classifications
A61K 9/1272
A61K 31/7105
Filing Date
2021-11-09
Application No.
17522754
Claims
23