PHARMACEUTICALLY ACCEPTABLE SALT AND CRYSTAL FORM OF TETRAHYDRONAPHTHALENE DERIVATIVE, AND PREPARATION METHOD
Application
US20260098027A1
Kind: A1
Apr 09, 2026
Inventors
Lina Jia, Junran YANG, Zhenxing DU, Lin WANG, Qiyun SHAO, Jun FENG
Abstract
The present invention relates to a pharmaceutically acceptable salt and a crystal form of a tetrahydronaphthalene derivative, and a preparation method. Specifically, the present disclosure provides a pharmaceutically acceptable salt and a crystal form of (S)-3-(5-(4-((1-(4-((1R,2R)-6-hydroxy-2-isobutyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine- 2,6-dione, and a preparation method therefor. The corresponding salt has good stability and can be better used for clinical treatment.
CPC Classifications
C07D 401/14
A61K 31/496
A61P 35/00
Filing Date
2023-09-28
Application No.
19112795