SYSTEMS, FORMULATIONS AND METHODS FOR GENERATING UNIVERSAL PEPTIDE/MHC COMPLEXES WITH ENGINEERED DISULFIDE CONNECTING THE HEAVY AND LIGHT CHAINS
Application
US20260097105A1
Kind: A1
Apr 09, 2026
Inventors
Nikolaos SGOURAKIS
Abstract
The present invention relates to engineering synthetic major histocompatibility complex (MHC) molecules for generating universal peptide/MHC complexes with engineered disulfide linkage(s) using structure-guided modeling and design and method for making and using the same.
CPC Classifications
A61K 39/001188
A61K 39/001191
A61K 39/385
A61P 35/00
C07K 14/4748
C07K 14/70539
A61K 2039/605
C07K 2319/00
Filing Date
2023-09-28
Application No.
19114130