FC VARIANTS
Application
US20260092115A1
Kind: A1
Apr 02, 2026
Inventors
Hitoshi KATADA, Kanako TATSUMI, Yutaka MATSUDA, Shun SHIMIZU, Masaki KAMIMURA, Yasunori KOMORI, Yuji HORI, Tomoyuki IGAWA, Hiroki KAWAUCHI, Hiroaki SUSUMU
Abstract
The present disclosure provides anti-CTLA-4 antibodies and methods of producing and using the antibodies. The present disclosure also provides nucleic acids encoding the anti-CTLA-4 antibodies and host cells containing the nucleic acids. Furthermore, the present disclosure provides polypeptides containing a variant Fc region and methods of producing and using the polypeptides.
CPC Classifications
C07K 16/2818
A61P 35/00
C12N 15/63
C07K 2317/24
C07K 2317/51
C07K 2317/52
C07K 2317/92
Filing Date
2025-12-03
Application No.
19407391